Animal-associated enterobacteria have dominated the genome sequencing arena for some time, but they represent only a fraction of the lifestyle diversity present in this family. Plant pathogenic enterobacteria, were totally unsampled until the Pectobacterium atrosepticum (Erwinia carotovora atroseptica) genome sequence was published in 2004. Currently GEL personnel and collaborators are working on genome projects for a number of additional plant-associated enterobacteria including Dickeya dadantii, Erwinia amylovora, Pantoea stewartii, Pectobacterium carotovorum, and Pectobacterium brasiliensis. Individually, each genome illuminates the biology of an agriculturally significant pathogen. Collectively, they provide an unprecedented opportunity to study evolution of host specialization and plant-microbe interaction.