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Dr. David Baumler PDF Print E-mail
Staff Scientist

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Staff Scientist

425G Henry Mall Suite 4400V
Madison, Wisconsin 53706

Phone: 608-890-0172
Email: This email address is being protected from spam bots, you need Javascript enabled to view it

Curriculum Vitae

Degrees and Training

  • B.S., Biochemistry; 1996, University of Wisconsin-Madison
  • M.S., Food Microbiology and Safety; 2000, University of Wisconsin-Madison
  • Ph.D., Cellular and Molecular Biology ; 2006, University of Wisconsin-Madison

Description

I joined the Enteropathogen Resource Integration Center ERIC in the fall of 2006. Having previously elucidated the sulfur pathway of an acidophilic archaeon and various acid tolerance mechanisms in E. coli O157:H7, I am focused on curation, analysis, and conservation of biochemical pathways and subsystems of the organisms  whose genomes comprise the ERIC database.  Additionally, I conduct various aspects of genome curation including: feature identification and creation, establishment of feature coordinates, analyzing and approving orthology and other sequence similarity-related relationships between features, and functional annotation of features using literature as well as other sources.  I am also the facilitator for educational outreach on the ERIC project.  Currently I am working in collaboration with the division of education of the American Society of Microbiology and the Scientific Education Alliance of the Howard Hughes Medical Institute to extend the use of the ERIC database to undergraduate educators as a tool for inquiry-based exercises to integrate bioinformatics throughout the undergraduate biology curriculum.

Publications

  • Baumler, D.J., Hung, K.F., Jeong, K.C., and C.W. Kaspar. 2008. Molybdate treatment and sulfate starvation decrease levels of ATP and DNA in "Ferroplasma acidarmanus". Archaea (in press).
  • Jeong, K.C., Hung, K.F., Baumler, D.J., Byrd, J.J., and C.W. Kaspar. 2008. Acid stress damage of DNA is prevented by Dps binding in Escherichia coli O157:H7. BMC Microbiology (in press).
  • Baumler, D.J., Hung, K.F., Cabot, E.C., Glasner, J.D., Greene, J.M., and N.T. Perna. 2008. Annotation of the bacteriophage 933W genome: an in-class interactive web-based exercise. Curriculum Resources Collection; http://www.microbelibrary.org/  (in press)
  • Glasner, J.D., G. Plunkett III, B.D. Anderson,  D.J. Baumler, B.S. Biehl, V. Burland,  E.C. Cabot, A.E. Darling, B. Mau, E.C. Neeno-Eckwall, D. Pot, Y. Qiu, A.I. Rissman, S. Worzella, S. Zaremba, J. Fedorko, P. Liss, M. Rusch, M. Shaker, L. Shaull, P. Shetty, J. Whitmore, F.R. Blattner, J.M. Greene, and N.T. Perna. 2007. Enteropathogen resource integration center (ERIC)-bioinformatics support for research on biodefense-relevant enterobacteria. Nucleic Acids Research 36:D519-523.  
  • Baumler, D.J. and C.W. Kaspar. 2007. Morphology of the acidophilic archaeon "Ferroplasma acidarmanus" strain fer1. Visual Collection; http://www.microbelibrary.org/ 
  • Baumler, D.J., K.F. Hung, K.C. Jeong, C.W. Kaspar. 2007. Production of methanethiol and volatile sulfur compounds by the archaeon "Ferroplasma acidarmanus". Extremophiles Oct. 4 [Epub ahead of print]. 
  • Erol, I., K.C Jeong, D.J. Baumler, B. Vykhodets, S.H. Choi, and C.W. Kaspar.  2006.  H-NS controls metabolism and stress tolerance in Escherichia coli O157:H7 that influence mouse passage. BMC Microbiology 6(1):72.
  • Baumler, D.J., K.F. Hung, J.L. Bose, B.M. Vykhodets, C.-M. Cheng, K.C. Jeong, and C.W. Kaspar.  2006. Enhancement of acid tolerance in Zymomonas mobilis by a proton-buffering peptide. Applied Biochemistry and Biotechnology 134(1):15-26.
  • Jeong, K.-C., D.J. Baumler, and C.W. Kaspar. 2006. dps expression in Escherichia coli O157:H7 requires an extended -10 region and is affected by the cAMP receptor protein.  Biochim Biophys Acta. 1759(1-2): 51-59.
  • Baumler, D.J., K.C. Jeong, B.G. Fox, J.F. Banfield, and C.W. Kaspar. 2005. Sulfate requirement for heterotrophic growth of the acidophilic archaeon “Ferroplasma acidarmanus” strain fer1.  Research in Microbiology 156(4): 492-498.
  • Macalady, J.L., M.M. Vestling, D.J. Baumler, N. Boekelheide, C.W. Kaspar, and J.F. Banfield.  2004. Tetraether-linked membrane monolayers in Ferroplasma spp.: a key to survival in acid. Extremophiles 8:411-419.
  • Choi, S-H., D.J. Baumler, and C. W. Kaspar.  2000.  Contribution of dps to Acid Stress Tolerance and oxidative stress tolerance in Escherichia coli O157:H7.  Applied and Environmental Microbiology. 66: 3911-3916.

 


Last Updated ( Thursday, 07 August 2008 )
 
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